Additive effects of acyclovir and immune transfer in neonatal herpes simplex virus infection in mice.
نویسنده
چکیده
Acyclovir had a dose-dependent, mild, but significant, inhibitory effect on interferon-stimulated human antiviral natural killer cytotoxicity in vitro. In a murine model of neonatal herpes simplex virus infection, acyclovir significantly (P < 0.05) increased survival afforded by the injection of human interferon and human mononuclear leukocytes from 67.8 to 88.6%.
منابع مشابه
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ورودعنوان ژورنال:
- Infection and immunity
دوره 39 1 شماره
صفحات -
تاریخ انتشار 1983